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InnovaBone biopolymers confirmed safe for use in tissue regeneration

InnovaBone partners the University of Valladolid, the Medical University of Vienna and the University of Vienna have been working closely together to evaluate biocompatibility and immunogenicity of Elastin-like recombinamers (ELRs). ELRs were created for use as a smart biomaterial for tissue engineering. They are designed to mimic elastin, a protein normally found in human tissues, which allows them to behave just like the constituents of the tissues in which they are integrated.
 
The three teams sought to establish a pre-clinical approach to evaluate biocompatibility in experimental mice using ELRs as a prototype biomaterial and achieved very promising results indicating that the ELRs are safe for use in tissue regeneration. These findings have recently been published in the Journal of Biomedical Materials Research - Part A
 
 

References: Changi K, Bosnjak B, Gonzalez-Obeso C, Kluger R, Rodríguez-Cabello JC, Hoffmann O, Epstein MM. 2017. Biocompatibility and immunogenicity of elastin-like recombinamer biomaterials in mouse models. J Biomed Mater Res Part A 2017:00A:000–000.

DOI: 10.1002/jbm.a.36290